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Clinical trial · no report yet · Phase 3

NCT06377852

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
Comparing Oral Drug Dosing Strategies in Older Patients With Metastatic Breast Cancer to Maximize Tolerance and Reduce Discontinuation: The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study
Phase
Phase 3
Status
Recruiting
Conditions
Metastatic Breast Cancer
Interventions
Palbociclib 125mg; Ribociclib 600mg; Ribociclib; Palbociclib
Arms
  • Arm 1: Indicated Dose · Experimental
  • Arm 2: Titrated Dose · Experimental
Enrollment
500 (estimated)
Primary outcomes
  • Time to Treatment Discontinuation (TTD)
Sponsor
American Society of Clinical Oncology with Patient-Centered Outcomes Research Institute
Start
Oct 29, 2024
Primary completion
Aug 31, 2028 (estimated)
Results posted
No
Registry record
NCT06377852 · updated Oct 6, 2026