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Clinical trial · no report yet · Phase 3

NCT06580314

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube9
Podcasts4

The trial

ClinicalTrials.gov
Official title
A Phase III Trial of One vs. Two Years of Maintenance Olaparib, With or Without Bevacizumab, in Patients With BRCA1/2 Mutated or Homologous Recombination Deficient (HRD+) Ovarian Cancer Following Response to First Line Platinum-Based Chemotherapy
Phase
Phase 3
Status
Recruiting
Conditions
Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube High Grade Serous Adenocarcinoma; Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor; FIGO Stage III Ovarian Cancer 2014; FIGO Stage IV Ovarian Cancer 2014; Ovarian Carcinoma; Ovarian Carcinosarcoma; Ovarian High Grade Endometrioid Adenocarcinoma; Ovarian High Grade Serous Adenocarcinoma; Primary Peritoneal Carcinosarcoma; Primary Peritoneal Endometrioid Adenocarcinoma; Primary Peritoneal High Grade Serous Adenocarcinoma
Interventions
Bevacizumab; Biospecimen Collection; Computed Tomography; Magnetic Resonance Imaging; Olaparib
Arms
  • Arm I (olaparib, bevacizumab) · Active comparator
  • Arm II (olaparib, bevacizumab) · Experimental
Enrollment
880 (estimated)
Primary outcomes
  • Progression free survival (PFS) at least 360 days after randomization (PFS360)
Sponsor
NRG Oncology with National Cancer Institute (NCI)
Start
Mar 12, 2025
Primary completion
Dec 31, 2034 (estimated)
Results posted
No
Registry record
NCT06580314 · updated Aug 7, 2026