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Clinical trial · no report yet · Phase 3

PACIFIC2

Study of Durvalumab Given With Chemoradiation Therapy in Patients With Unresectable Non-small Cell Lung Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads120
Podcasts31
YouTube21

The trial

ClinicalTrials.gov
Official title
A Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Given Concurrently With Platinum-based Chemoradiation Therapy in Patients With Locally Advanced, Unresectable NSCLC (Stage III) (PACIFIC2)
Phase
Phase 3
Status
Completed
Conditions
Non-Small Cell Lung Cancer
Interventions
Durvalumab; Placebo; Cisplatin/ Etoposide; Carboplatin/ Paclitaxel; Pemetrexed/ Cisplatin; Pemetrexed/ Carboplatin; Radiation
Arms
  • Arm 1: Durvalumab + platinum-based chemotherapy and radiation · Experimental
  • Arm 2: Placebo + platinum-based chemotherapy and radiation · Placebo comparator
Enrollment
328
Primary outcomes
  • Progression-Free Survival (PFS)
Sponsor
AstraZeneca
Start
Mar 29, 2018
Primary completion
Sep 7, 2023
Results posted
Yes
Registry record
NCT03519971 · updated Jul 14, 2026