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Clinical trial · no report yet · Phase 3

RASolve 301

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

  • NCT06881784 ↗
  • Recruiting
  • Revolution Medicines, Inc.
  • 3 commentary sources found
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.

ChannelFound
X threads2
Podcasts1

The trial

ClinicalTrials.gov
Official title
RASolve 301: Phase 3 Multicenter, Open Label, Randomized Study of RMC-6236 Versus Docetaxel in Patients With Previously Treated Locally Advanced or Metastatic RAS[MUT] NSCLC
Phase
Phase 3
Status
Recruiting
Conditions
NSCLC (Non-small Cell Lung Cancer); Non-Small Cell Lung Cancer; NSCLC; NSCLC (Non-small Cell Lung Carcinoma); NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions
daraxonrasib; docetaxel
Arms
  • daraxonrasib · Experimental
  • docetaxel · Active comparator
Enrollment
590 (estimated)
Primary outcomes
  • Progression free survival (PFS) per Blinded Independent Central Review (BICR) in the RAS G12X-C population (i.e RAS G12X excluding G12C)
  • Overall survival (OS) in the RAS G12X-C population
Sponsor
Revolution Medicines, Inc.
Start
May 6, 2025
Primary completion
Dec 1, 2027 (estimated)
Results posted
No
Registry record
NCT06881784 · updated Sep 29, 2026