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Clinical trial · no report yet · Phase 2

SACTION 01

SBRT Followed by Neoadjuvant Immunochemotherapy in Resectable Stage II to III Non-small Cell Lung Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
Preoperative Stereotactic Body Radiotherapy and Platinum-based Doublet Chemotherapy Plus Tislelizumab (Immunotherapy) for Operable Stage II to III EGFR Wild-type Non-small Cell Lung Cancer
Phase
Phase 2
Status
Active, not recruiting
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
SBRT; Tislelizumab
Arms
  • Neoadjuvant SBRT plus immunochemotherapy · Experimental
Enrollment
46 (estimated)
Primary outcomes
  • Major Pathological Response (MPR)
Sponsor
Sun Yat-sen University
Start
Apr 24, 2022
Primary completion
Jun 25, 2023
Results posted
No
Registry record
NCT05319574 · updated Oct 13, 2026

Publications

linked from the registry
  • Zhao ZR, Liu SL, Zhou T, Chen G, Long H, Su XD, Zhang X, Fu JH, Lin P, Zhang LJ, Rong TH, Wu JD, Li ZC, Su HL, Chen JY, Yang YP, Lin YB, Xi M, Yang H. Stereotactic body radiotherapy with sequential tislelizumab and chemotherapy as neoadjuvant therapy in patients with resectable non-small-cell lung cancer in China (SACTION01): a single-arm, single-centre, phase 2 trial. Lancet Respir Med. 2024 Dec;12(12):988-996. doi: 10.1016/S2213-2600(24)00215-7. Epub 2024 Sep 18. PubMed 39305910