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Clinical trial · no report yet · Phase 2

VICCURO21103

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads18
YouTube8
Podcasts4

The trial

ClinicalTrials.gov
Official title
Optimal Treatment by Invoking Biologic Clusters in Renal Cell Carcinoma (OPTIC RCC)
Phase
Phase 2
Status
Recruiting
Conditions
Advanced Clear Cell Renal Cell Carcinoma; Metastatic Clear Cell Renal Cell Carcinoma; Stage III Renal Cell Cancer AJCC v8; Stage IV Renal Cell Cancer AJCC v8
Interventions
Cabozantinib; Ipilimumab; Nivolumab
Arms
  • Arm I (ipilimumab, nivolumab) · Experimental
  • Arm II (nivolumab, cabozantinib) · Experimental
Enrollment
54 (estimated)
Primary outcomes
  • Overall response rate (ORR) (Arm 1)
  • Overall response rate (Arm 2)
Sponsor
Vanderbilt-Ingram Cancer Center with National Cancer Institute (NCI), United States Department of Defense
Start
Dec 6, 2022
Primary completion
Oct 1, 2027 (estimated)
Results posted
No
Registry record
NCT05361720 · updated Aug 19, 2026