ACT-1

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Screened window

Mar 2, 2019 → Oct 25, 2026

Cited window

Mar 2, 2019 → Jun 14, 2023

Retrieved

Oct 31, 2026

Title

A Randomized Phase III Study to Evaluate the Efficacy of Chemoimmunotherapy With the Monoclonal Antibody Campath-1H (Alemtuzumab) Given in Combination With 2-weekly CHOP Versus 2-weekly CHOP Alone and Consolidated by Autologous Stem Cell Transplant, in Young Patients With Previously Untreated Systemic Peripheral T-cell Lymphomas

Registry

NCT00646854

Study IDs

2006-006130-17

Sponsor

Aarhus University Hospital

Collaborators

GCP-unit at Aarhus University Hospital, Aarhus, Denmark

Design

Phase 3 · Interventional, randomized, parallel

Status

Completed

Enrollment

136 actual

Registered

2008-03-31

Start

2008-06 actual

Primary completion

2016-12-31 actual

Primary endpoint

Event-free Survival

Interventions

2 registered

This report does not judge efficacy, estimate HCP prevalence or consensus or give treatment advice.

• –Discussion that does not name the trial may be missing from this edition.
• –Some passages in the sources used in this report were not fully assessed for clinician views, so a view there may be missing from this edition.
• –2 statements in the sources reviewed for this edition are about other patients or topics, or only mention the trial, and are not counted.
• –Further source limits: discussion that describes the trial without naming it may be incomplete; some discussion that describes the trial without naming it may be missing; sources about other trials are not included.
• –The findings rest on two short X posts. Relevant discussion that does not name the trial may be missing, and two passages were not fully assessed for clinician views.
• –No results publication for NCT00646854 or trial protocol was available among the sources reviewed for this edition; the posts cannot substitute for a trial-specific quantitative assessment.
• –The survival statement lacks an identified endpoint, time point and estimate; the relayed response-rate statement lacks an identified study, numerical rate, definition and time point.
• –These statements do not establish treatment recommendations, safety reassurance, stem-cell-harvest feasibility or agreement across HCPs.

How reports are built and checked: Methods.

Last checked for new commentary Oct 31, 2026. A new or changed finding gets a new version number; added evidence alone is a smaller update. No corrections.

Paste this into ChatGPT, Claude, Microsoft Copilot or your own agent. It previews this report through the free Erudio MCP server, tells you whether it answers your question, and orders it if you ask. Some agents ask you to confirm pasted instructions before acting; that is expected.

Help me decide whether to buy the Erudio report "ACT-1" (NCT00646854), and buy it for me if I ask. Erudio reports cover what clinicians say in public about one clinical trial, with every verified statement linked to its source.

1. Use the free Erudio MCP server at https://mcp.erudio.com/free; it needs no sign-in. Nothing needs installing: if it is not connected in this app and you can make HTTP requests, call it directly with JSON-RPC POSTs to that URL (initialize, then tools/call), sending "Accept: application/json, text/event-stream". Call get_report_card with slug "act-1-00646854". If you cannot make requests, read https://www.erudio.com/reports/act-1-nct00646854.md instead.
2. In a few lines, tell me what the report covers: its findings, its verified statements and sources, its evidence window, what it leaves out, and the price of each product (offer). Then ask what I need it for, and say plainly whether this report answers it.
3. If I want it, ask for my work email and the product: the current edition, or 3, 6 or 12 months of weekly updates. Call create_order with report "NCT00646854", that product and email, then show me the quote and the checkout_url to pay by card. If you have a payment client for HTTP 402 payments and I agree, you can pay the pay_url instead. Nothing is charged until one is paid.
4. Once it is paid, call get_order with the status_url: it returns my license key. Then use the Erudio MCP server at https://mcp.erudio.com/mcp with the header "Authorization: Bearer <key>". Call read_report with report_id erudio-nct00646854 and sections ["all"], and summarize the findings for me with their sources. The full report is large (about 500 KB): save the response to a file and work from it rather than printing it. If you cannot, read sections ["narratives"] first, the executive summary and analysis.

When you tell me what clinicians said, give each view as theirs, with its source. Counts are the sources the report kept, not the share of clinicians who agree. Reports are not medical advice.
Keep the key private to my organization.

curl https://www.erudio.com/reports/act-1-nct00646854.json
curl https://www.erudio.com/reports/act-1-nct00646854.md

# MCP, no sign-in (https://mcp.erudio.com/free)
get_report_card({ "slug": "act-1-00646854" })