DEWI

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Jan 15, 2025 → Oct 26, 2026

Cited window

Oct 20, 2026 → Oct 25, 2026

Retrieved

Oct 29, 2026

Title

Watch-and-wait Strategy to Initiate Dostarlimab-based Immunotherapy in Localized Deficient Mismatch Repair (dMMR) and/or Microsatellite Instability High (MSI-H) oEso-gastric Junction and Gastric Adenocarcinoma: An Open-label GERCOR Phase II Study

Registry

NCT06059495

Study IDs

DEWI G-123 · 2023-506102-39-00 (EU CT)

Sponsor

GERCOR - Multidisciplinary Oncology Cooperative Group

Design

Phase 2 · Interventional, single group

Status

Recruiting

Enrollment

89 estimated

Registered

2023-09-28

Start

2024-01-22 actual

Primary completion

2028-09-01 estimated

Primary endpoint

Clinical complete response (cCR)

Interventions

1 registered

This report does not judge efficacy, estimate HCP prevalence or consensus or give treatment advice.

• –Discussion that does not name the trial may be missing from this edition.
• –1 matching source (1 X thread) could not be read and is not included.
• –Some passages in the sources used in this report were not fully assessed for clinician views, so a view there may be missing from this edition.
• –17 statements in the sources reviewed for this edition are about other patients or topics, or only mention the trial, and are not counted.
• –Further source limits: discussion that describes the trial without naming it may be incomplete; some discussion that describes the trial without naming it may be missing; sources about other trials are not included.
• –This is not a complete survey of public discussion or clinician opinion. Some potentially relevant passages were not fully assessed, one discussion was unavailable, and unnamed references or alternative spellings may be missing.
• –No trial-specific results publication or protocol was available for direct comparison. A dostarlimab regulatory label was also unavailable; these sources do not establish approved use.
• –The cited 24-patient first-interim analysis and 43-patient summary have different denominators and follow-up. Their juxtaposition does not establish a change in efficacy over time.
• –Reports of no relapse or death concern the specified complete responders at the stated follow-up. They should not be generalized to all treated patients or interpreted as cure.
• –Repeated abstract information, reposts, institutional wording and a linked article summary are not additional independent HCP opinions.
• –One author is unnamed; that author's clinical role is not established in the sources reviewed for this edition. Credentials described by sources for some other authors are not independently confirmed clinical roles.

How reports are built and checked: Methods.

Last checked for new commentary Oct 29, 2026. A new or changed finding gets a new version number; added evidence alone is a smaller update. No corrections.

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get_report_card({ "slug": "dewi-06059495" })