STAR-TREC

An aspect marked incomplete is a question the public commentary did not let us answer. We show it rather than hide it.

Screened window

May 1, 2016 → Oct 29, 2026

Cited window

May 13, 2016 → Oct 23, 2026

Retrieved

Oct 31, 2026

Title

STAR-TREC: Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer?

Registry

NCT02945566

Study IDs

RG_15-011 · 2016-000862-49

Sponsor

University of Birmingham

Design

Phase 2/Phase 3 · Interventional, randomized, parallel

Status

Active, not recruiting

Enrollment

380 estimated

Registered

2016-10-26

Start

2017-06-14 actual

Primary completion

2027-08 estimated

Primary endpoint

Phase II (Feasibility study) Primary Outcome: Recruitment Rate

Interventions

3 registered

This report does not judge efficacy, estimate HCP prevalence or consensus or give treatment advice.

• –Discussion that does not name the trial may be missing from this edition.
• –Not yet captured in this edition: a question about evidence for low alpha/beta in rectal cancer and its possible implications for radiotherapy fractionation.
• –Some passages in the sources used in this report were not fully assessed for clinician views, so a view there may be missing from this edition.
• –94 statements in the sources reviewed for this edition are about other patients or topics, or only mention the trial, and are not counted.
• –Further source limits: discussion that describes the trial without naming it may be incomplete; some discussion that describes the trial without naming it may be missing; sources about other trials are not included.
• –The report describes the sources reviewed for this edition, not all HCPs or all public discussion; discussion frequency and source numbers cannot establish clinician consensus.
• –A complete text was unavailable for one review of local versus radical surgery. Its conclusions should not be treated as a comprehensive account of every underlying study.
• –The directly included results paper concerns radiotherapy planning. Early clinical comparisons are conveyed through attributed commentary and a linked article summary; those sources do not establish mature 30-month clinical outcomes.
• –Individual opinions, relayed presentations, institutional communication and patient anecdotes are different kinds of evidence. Reposting does not establish independent endorsement.
• –Clinical roles are unstated or unconfirmed for several named authors. Descriptions of credentials, trial participation or leadership remain attributed to their sources, and do not increase the evidentiary weight of a view.
• –Several video passages cannot be assigned to a named speaker from the spoken material. Captions, publisher descriptions and a named person elsewhere in the recording do not resolve those passages.
• –Endpoint and population labels are inconsistent in some comments, including a speaker's 18% and approximately 25% statements and another speaker's locally advanced description and numerical characterization. They are preserved as statements, not silently corrected.
• –Comparisons involving TREC, OPERA, WW2, NEO, TOWARd, RAPIDO and retrospective series retain their own settings and uncertainties. They are not STAR-TREC results or proof that their populations and regimens are interchangeable.
• –Post dates and recruitment updates do not establish readout dates, changes of mind, current practice prevalence or confirmed guideline change.

How reports are built and checked: Methods.

Last checked for new commentary Oct 31, 2026. A new or changed finding gets a new version number; added evidence alone is a smaller update. No corrections.

Paste this into ChatGPT, Claude, Microsoft Copilot or your own agent. It previews this report through the free Erudio MCP server, tells you whether it answers your question, and orders it if you ask. Some agents ask you to confirm pasted instructions before acting; that is expected.

Help me decide whether to buy the Erudio report "STAR-TREC" (NCT02945566), and buy it for me if I ask. Erudio reports cover what clinicians say in public about one clinical trial, with every verified statement linked to its source.

1. Use the free Erudio MCP server at https://mcp.erudio.com/free; it needs no sign-in. Nothing needs installing: if it is not connected in this app and you can make HTTP requests, call it directly with JSON-RPC POSTs to that URL (initialize, then tools/call), sending "Accept: application/json, text/event-stream". Call get_report_card with slug "star-trec-02945566". If you cannot make requests, read https://www.erudio.com/reports/star-trec-nct02945566.md instead.
2. In a few lines, tell me what the report covers: its findings, its verified statements and sources, its evidence window, what it leaves out, and the price of each product (offer). Then ask what I need it for, and say plainly whether this report answers it.
3. If I want it, ask for my work email and the product: the current edition, or 3, 6 or 12 months of weekly updates. Call create_order with report "NCT02945566", that product and email, then show me the quote and the checkout_url to pay by card. If you have a payment client for HTTP 402 payments and I agree, you can pay the pay_url instead. Nothing is charged until one is paid.
4. Once it is paid, call get_order with the status_url: it returns my license key. Then use the Erudio MCP server at https://mcp.erudio.com/mcp with the header "Authorization: Bearer <key>". Call read_report with report_id erudio-nct02945566 and sections ["all"], and summarize the findings for me with their sources. The full report is large (about 500 KB): save the response to a file and work from it rather than printing it. If you cannot, read sections ["narratives"] first, the executive summary and analysis.

When you tell me what clinicians said, give each view as theirs, with its source. Counts are the sources the report kept, not the share of clinicians who agree. Reports are not medical advice.
Keep the key private to my organization.

curl https://www.erudio.com/reports/star-trec-nct02945566.json
curl https://www.erudio.com/reports/star-trec-nct02945566.md

# MCP, no sign-in (https://mcp.erudio.com/free)
get_report_card({ "slug": "star-trec-02945566" })