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Clinical trial · no report yet · Phase 3
AHOD0431
Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma
- NCT00302003 ↗
- Completed
- Children's Oncology Group
- Focused
We haven't built an HCP commentary report on AHOD0431 (doxorubicin plus vincristine plus cyclophosphamide plus prednisone in early-stage, low-risk pediatric Hodgkin lymphoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on AHOD0431 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 6 |
The trial
ClinicalTrials.gov- Official title
- A Phase III Study for the Treatment of Children and Adolescents With Newly Diagnosed Low Risk Hodgkin Disease
- Phase
- Phase 3
- Status
- Completed
- Conditions
- Childhood Favorable Prognosis Hodgkin Lymphoma; Childhood Lymphocyte Depletion Hodgkin Lymphoma; Childhood Mixed Cellularity Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage II Childhood Hodgkin Lymphoma
- Interventions
- radiation therapy; doxorubicin hydrochloride; vincristine sulfate; prednisone; cyclophosphamide; ifosfamide; vinorelbine tartrate; dexamethasone; etoposide phosphate; cisplatin; cytarabine; filgrastim
- Arms
- Doxorubicin, Vincristine, Cyclophosphamide and Filgrastim · Experimental
- Enrollment
- 287
- Primary outcomes
- Event Free Survival Without Receiving Radiation Therapy (EFSnoRT).
- Intensive Therapy Free Survival (ITFS).
- Event Free Survival (EFS)
- Sponsor
- Children's Oncology Group with National Cancer Institute (NCI)
- Start
- Feb 2006
- Primary completion
- Mar 2012
- Results posted
- Yes
- Registry record
- NCT00302003 · updated Mar 30, 2021
Publications
linked from the registry- Castellino SM, Giulino-Roth L, Harker-Murray P, Kahn JM, Forlenza C, Cho S, Hoppe B, Parsons SK, Kelly KM; COG Hodgkin Lymphoma Committee. Children's Oncology Group's 2023 blueprint for research: Hodgkin lymphoma. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30580. doi: 10.1002/pbc.30580. Epub 2023 Jul 28. PubMed 37505794
- Parekh A, Keller FG, McCarten KM, Kessel S, Cho S, Pei Q, Wu Y, Castellino SM, Constine LS, Schwartz CL, Hodgson D, Kelly KM, Hoppe BS. Targeted radiotherapy for early-stage, low-risk pediatric Hodgkin lymphoma slow early responders: a COG AHOD0431 analysis. Blood. 2022 Sep 8;140(10):1086-1093. doi: 10.1182/blood.2022016098. PubMed 35763667