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Clinical trial · no report yet · Phase 3

ATALANTE

ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+Bevacizumab

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads5
Podcasts2

The trial

ClinicalTrials.gov
Official title
A Randomized, Double-blinded, Phase III Study of Atezolizumab Versus Placebo in Patients With Late Relapse of Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer Treated by Platinum-based Chemotherapy and Bevacizumab
Phase
Phase 3
Status
Completed
Conditions
Ovarian Cancer
Interventions
atezolizumab + avastin + platinum-based chemotherapy; placebo + avastin + platinum-based chemotherapy
Arms
  • Arm A: Placebo + Avastin + platinum-based chemotherapy · Placebo comparator
  • Arm B: Atezolizumab + Avastin+ platinum-based chemotherapy · Experimental
Enrollment
614
Primary outcomes
  • Efficacy: Progression free survival, where the date of progression is based on investigator assessment using the RECIST version 1.1
Sponsor
ARCAGY/ GINECO GROUP with Hoffmann-La Roche
Start
Sep 22, 2016
Primary completion
Oct 15, 2021
Results posted
No
Registry record
NCT02891824 · updated Feb 11, 2025

Publications

linked from the registry
  • Kurtz JE, Pujade-Lauraine E, Oaknin A, Belin L, Leitner K, Cibula D, Denys H, Rosengarten O, Rodrigues M, de Gregorio N, Martinez Garcia J, Petru E, Kocian R, Vergote I, Pautier P, Schmalfeldt B, Gaba L, Polterauer S, Mouret Reynier MA, Sehouli J, Churruca C, Selle F, Joly F, D'Hondt V, Bultot-Boissier E, Lebreton C, Lotz JP, Largillier R, Heudel PE, Heitz F; ATALANTE/ENGOT-ov29 Investigators. Atezolizumab Combined With Bevacizumab and Platinum-Based Therapy for Platinum-Sensitive Ovarian Cancer: Placebo-Controlled Randomized Phase III ATALANTE/ENGOT-ov29 Trial. J Clin Oncol. 2023 Oct 20;41(30):4768-4778. doi: 10.1200/JCO.23.00529. Epub 2023 Aug 29. PubMed 37643382