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Clinical trial · no report yet · Phase 3

BOND-003

Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin

  • NCT04452591 ↗
  • Active not recruiting
  • CG Oncology, Inc.
  • 57 commentary sources found
  • Deep

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads36
Podcasts12
YouTube9

The trial

ClinicalTrials.gov
Official title
A Phase 3 Study of Cretostimogene Grenadenorepvec in Patients With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus-Calmette-Guerin (BCG)
Phase
Phase 3
Status
Active not recruiting
Conditions
Non Muscle Invasive Bladder Cancer; High-grade Ta/ T1 Papillary Disease Bladder Cancer
Interventions
Cretostimogene Grenadenorepvec; n-dodecyl-B-D-maltoside
Arms
  • Cohort C(All Countries):Enrollment Closed · Experimental
  • Cohort P(Japan and United States Only) :Open to Enrollment · Experimental
Enrollment
190 (estimated)
Primary outcomes
  • Cohort C:
  • Cohort P:
Sponsor
CG Oncology, Inc.
Start
Oct 27, 2020
Primary completion
Jun 16, 2030 (estimated)
Results posted
No
Registry record
NCT04452591 · updated Jul 10, 2026

Publications

linked from the registry
  • Tyson MD 2nd, Nam JK, Joshi SS, Uchio EM, Jung SI, Bivalacqua TJ, Steinberg GD, Shore ND, Burke JM, Kitamura H, Tran B, Li R. Intravesical cretostimogene grenadenorepvec oncolytic immunotherapy in high-risk, BCG-unresponsive, non-muscle-invasive bladder cancer with carcinoma in situ (BOND-003 Cohort C): a single-arm, phase 3 trial. Lancet Oncol. 2026 Aug;27(8):983-993. doi: 10.1016/S1470-2045(26)00194-4. PubMed 42508433