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Clinical trial · no report yet · Phase 2
BULLSEYE trial: what clinicians have said so far
Lutetium-177-PSMA-617 in Oligo-metastatic Hormone Sensitive Prostate Cancer
- NCT04443062 ↗
- Completed
- Radboud University Medical Center
- Deep size, estimated: 301+ verified statements once built
We haven't built an HCP commentary report on BULLSEYE (177Lu-PSMA-617 in oligometastatic hormone-sensitive prostate cancer) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on BULLSEYE so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Indexed so far | |
|---|---|
| 28 posts on X, typically up to 123 once built | |
| 5 YouTube videos, typically up to 22 once built | |
| 1 podcast episode, typically up to 4 once built |
The trial
ClinicalTrials.gov- Official title
- Lutetium-177-PSMA-617 Radioligand Therapy in Oligo-metastatic Hormone Sensitive Prostate Cancer.
- Phase
- Phase 2
- Status
- Completed
- Conditions
- Prostate Cancer
- Interventions
- 177Lu-PSMA-617
- Arms
- Interventional arm: 177Lu-PSMA radioligand therapy · Experimental
- Standard of care · No intervention
- Enrollment
- 58
- Primary outcomes
- To compare the fraction of patients that have disease progression (and meet EOT 1) criteria within 6 months in a group of patients that are treated with 177Lu-PSMA and a group that follows the current standard of care.
- A second primary aim is to compare the two arms for the time to disease progression and meeting EOT 1 criteria.
- Sponsor
- Radboud University Medical Center with Prostaatkankerstichting, Advanced Accelerator Applications
- Start
- Jul 20, 2020
- Primary completion
- Apr 1, 2025
- Results posted
- No
- Registry record
- NCT04443062 · updated Feb 27, 2026
Publications
linked from the registry- Rahbar K, Ahmadzadehfar H, Kratochwil C, Haberkorn U, Schafers M, Essler M, Baum RP, Kulkarni HR, Schmidt M, Drzezga A, Bartenstein P, Pfestroff A, Luster M, Lutzen U, Marx M, Prasad V, Brenner W, Heinzel A, Mottaghy FM, Ruf J, Meyer PT, Heuschkel M, Eveslage M, Bogemann M, Fendler WP, Krause BJ. German Multicenter Study Investigating 177Lu-PSMA-617 Radioligand Therapy in Advanced Prostate Cancer Patients. J Nucl Med. 2017 Jan;58(1):85-90. doi: 10.2967/jnumed.116.183194. Epub 2016 Oct 20. PubMed 27765862
- Hofman MS, Violet J, Hicks RJ, Ferdinandus J, Thang SP, Akhurst T, Iravani A, Kong G, Ravi Kumar A, Murphy DG, Eu P, Jackson P, Scalzo M, Williams SG, Sandhu S. [177Lu]-PSMA-617 radionuclide treatment in patients with metastatic castration-resistant prostate cancer (LuPSMA trial): a single-centre, single-arm, phase 2 study. Lancet Oncol. 2018 Jun;19(6):825-833. doi: 10.1016/S1470-2045(18)30198-0. Epub 2018 May 8. PubMed 29752180
- Prive BM, Noordzij W, Muselaers CHJ, de Jong IJ, van Oort IM, Janssen MJR, Van Rijk MC, van Gemert WA, Timmermans B, de Groot M, Mehra N, Gerritsen WR, Jonker MA, Alevroudis E, van der Gaag S, Koppes JCC, Sedelaar JPM, Vis AN, Vrachimis A, Oprea-Lager DE, Nagarajah J. [177Lu]-PSMA-617-PSMA-617 in oligometastatic hormone sensitive prostate cancer (BULLSEYE): an open-label, randomised, phase 2 study. Lancet Oncol. 2026 Apr;27(4):461-469. doi: 10.1016/S1470-2045(25)00762-4. PubMed 41926960
- Prive BM, Janssen MJR, van Oort IM, Muselaers CHJ, Jonker MA, van Gemert WA, de Groot M, Westdorp H, Mehra N, Verzijlbergen JF, Scheenen TWJ, Zamecnik P, Barentsz JO, Gotthardt M, Noordzij W, Vogel WV, Bergman AM, van der Poel HG, Vis AN, Oprea-Lager DE, Gerritsen WR, Witjes JA, Nagarajah J. Update to a randomized controlled trial of lutetium-177-PSMA in Oligo-metastatic hormone-sensitive prostate cancer: the BULLSEYE trial. Trials. 2021 Nov 4;22(1):768. doi: 10.1186/s13063-021-05733-4. PubMed 34736509
- Prive BM, Janssen MJR, van Oort IM, Muselaers CHJ, Jonker MA, de Groot M, Mehra N, Verzijlbergen JF, Scheenen TWJ, Zamecnik P, Barentsz JO, Gotthardt M, Noordzij W, Vogel WV, Bergman AM, van der Poel HG, Vis AN, Oprea-Lager DE, Gerritsen WR, Witjes JA, Nagarajah J. Lutetium-177-PSMA-I&T as metastases directed therapy in oligometastatic hormone sensitive prostate cancer, a randomized controlled trial. BMC Cancer. 2020 Sep 14;20(1):884. doi: 10.1186/s12885-020-07386-z. PubMed 32928177