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Clinical trial · no report yet · Phase 2

CaboPoint

Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
X threads20
YouTube8
Podcasts8

The trial

ClinicalTrials.gov
Official title
A Phase II, Multicentre, Open-label Study of Cabozantinib as 2nd Line Treatment in Subjects With Unresectable, Locally Advanced or Metastatic Renal Cell Carcinoma With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors.
Phase
Phase 2
Status
Completed
Conditions
Locally Advanced or Metastatic Renal Cell Carcinoma
Interventions
Cabozantinib
Arms
  • Cohort A · Experimental
  • Cohort B · Experimental
Enrollment
127
Primary outcomes
  • Cohort A: Objective Response Rate (ORR) Assessed by Independent Central Review
Sponsor
Ipsen
Start
Jan 8, 2020
Primary completion
May 11, 2023
Results posted
Yes
Registry record
NCT03945773 · updated Oct 6, 2026

Publications

linked from the registry
  • Albiges L, Schmidinger M, Taguieva-Pioger N, Perol D, Grunwald V, Guemas E. CaboPoint: a phase II study of cabozantinib as second-line treatment in patients with metastatic renal cell carcinoma. Future Oncol. 2022 Mar;18(8):915-926. doi: 10.2217/fon-2021-1006. Epub 2021 Dec 16. PubMed 34911359