Clinical trial · no report yet · Phase 2
CAPELA
PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)
- NCT07222215 ↗
- Recruiting
- Kristina A. Fanucci
- Focused
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| Podcasts | 2 | |
| Bluesky threads | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase II Multi-Center Open-label Randomized Study of CAPecitabine in Combination With ELAcestrant Versus Capecitabine Alone in Advanced Estrogen Receptor-Positive Breast Cancer (CAPELA)
- Phase
- Phase 2
- Status
- Recruiting
- Conditions
- Estrogen-receptor-positive Breast Cancer; Metastatic Breast Cancer; Breast Cancer; Hormone Receptor Positive Breast Cancer; Human Epidermal Growth Factor 2 Negative Carcinoma of Breast; HER2- Breast Cancer; ESR1 Gene Mutation; ER Wildtype; Breast Neoplasms
- Interventions
- Capecitabine; Elacestrant
- Arms
- Arm A: Capecitabine + Elacestrant · Experimental
- Arm B: Capecitabine Monotherapy · Experimental
- Optional switch after progression on Arm B Capecitabine monotherapy: Elacestrant Monotherapy · Experimental
- Enrollment
- 297 (estimated)
- Primary outcomes
- Progression Free Survival (PFS) in ESR1 mutant population
- Progression Free Survival (PFS) in intention to treat (ITT) population
- Sponsor
- Kristina A. Fanucci with Stemline Therapeutics, Inc., Johns Hopkins University, Translational Breast Cancer Research Consortium, Menarini Group, Gateway for Cancer Research, Terri Brodeur Breast Cancer Foundation
- Start
- Jan 16, 2026
- Primary completion
- Dec 1, 2029 (estimated)
- Results posted
- No
- Registry record
- NCT07222215 · updated Aug 26, 2026