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Clinical trial · no report yet · Phase 3
COG-AHOD0431
Combination Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Lymphoma
- NCT00302003 ↗
- Completed
- Children's Oncology Group
- Focused
We haven't built an HCP commentary report on COG-AHOD0431 (doxorubicin hydrochloride, vincristine sulfate and 9 more in Childhood Favorable Prognosis Hodgkin Lymphoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on COG-AHOD0431 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 6 |
The trial
ClinicalTrials.gov- Official title
- A Phase III Study for the Treatment of Children and Adolescents With Newly Diagnosed Low Risk Hodgkin Disease
- Phase
- Phase 3
- Status
- Completed
- Conditions
- Childhood Favorable Prognosis Hodgkin Lymphoma; Childhood Lymphocyte Depletion Hodgkin Lymphoma; Childhood Mixed Cellularity Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin Lymphoma; Stage I Childhood Hodgkin Lymphoma; Stage II Childhood Hodgkin Lymphoma
- Interventions
- radiation therapy; doxorubicin hydrochloride; vincristine sulfate; prednisone; cyclophosphamide; ifosfamide; vinorelbine tartrate; dexamethasone; etoposide phosphate; cisplatin; cytarabine; filgrastim
- Arms
- Doxorubicin, Vincristine, Cyclophosphamide and Filgrastim · Experimental
- Enrollment
- 287
- Primary outcomes
- Event Free Survival Without Receiving Radiation Therapy (EFSnoRT).
- Intensive Therapy Free Survival (ITFS).
- Event Free Survival (EFS)
- Sponsor
- Children's Oncology Group with National Cancer Institute (NCI)
- Start
- Feb 2006
- Primary completion
- Mar 2012
- Results posted
- Yes
- Registry record
- NCT00302003 · updated Mar 30, 2021
Publications
linked from the registry- Castellino SM, Giulino-Roth L, Harker-Murray P, Kahn JM, Forlenza C, Cho S, Hoppe B, Parsons SK, Kelly KM; COG Hodgkin Lymphoma Committee. Children's Oncology Group's 2023 blueprint for research: Hodgkin lymphoma. Pediatr Blood Cancer. 2023 Sep;70 Suppl 6(Suppl 6):e30580. doi: 10.1002/pbc.30580. Epub 2023 Jul 28. PubMed 37505794
- Parekh A, Keller FG, McCarten KM, Kessel S, Cho S, Pei Q, Wu Y, Castellino SM, Constine LS, Schwartz CL, Hodgson D, Kelly KM, Hoppe BS. Targeted radiotherapy for early-stage, low-risk pediatric Hodgkin lymphoma slow early responders: a COG AHOD0431 analysis. Blood. 2022 Sep 8;140(10):1086-1093. doi: 10.1182/blood.2022016098. PubMed 35763667