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Clinical trial · no report yet · Phase 2/Phase 3

DIAL

De-escalation Immunotherapy mAintenance Duration Trial for Stage IV Lung Cancer Patients With Disease Control After Chemo-immunotherapy Induction

  • NCT05255302 ↗
  • Recruiting
  • Intergroupe Francophone de Cancerologie Thoracique
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads9

The trial

ClinicalTrials.gov
Official title
A Phase II-III Randomized Trial Evaluating Maintenance Pembrolizumab (± Pemetrexed) Until Progression Versus Observation (± Pemetrexed) After 6 Months of Platinum-based Doublet Chemotherapy Plus Pembrolizumab Induction Treatment in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)
Phase
Phase 2/Phase 3
Status
Recruiting
Conditions
Metastatic NSCLC
Interventions
Pembrolizumab before randomization; Chemotherapy; Pemetrexed; Pembrolizumab after randomization
Arms
  • Arm A : control Arm · Active comparator
  • Arm B : experimental arm · Experimental
Enrollment
1,360 (estimated)
Primary outcomes
  • Phase II: 18-month overall survival (OS)
  • Phase III: overall survival
Sponsor
Intergroupe Francophone de Cancerologie Thoracique
Start
May 2, 2022
Primary completion
May 2025 (estimated)
Results posted
No
Registry record
NCT05255302 · updated Apr 1, 2025