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Clinical trial · no report yet · Phase 3
E3A06
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
- NCT01169337 ↗
- Active, not recruiting
- National Cancer Institute (NCI)
- Deep
We haven't built an HCP commentary report on E3A06 (lenalidomide in Light Chain Deposition Disease) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on E3A06 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 72 | |
| YouTube | 2 | |
| Podcasts | 2 |
The trial
ClinicalTrials.gov- Official title
- Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
- Phase
- Phase 3
- Status
- Active, not recruiting
- Conditions
- Light Chain Deposition Disease; Smoldering Multiple Myeloma
- Interventions
- Clinical Observation; Lenalidomide; Quality-of-Life Assessment
- Arms
- Arm A (lenalidomide) · Experimental
- Arm B (observation) · Active comparator
- Enrollment
- 226
- Primary outcomes
- Proportion of Patients With Grade 3 Adverse Events That Effect Vital Organ Function or Any Grade 4 or Higher Non-hematologic Adverse Events (Phase II Primary Endpoint)
- 2-year Progression-free Survival (PFS) Rate (Phase III Primary Endpoint)
- Sponsor
- National Cancer Institute (NCI)
- Start
- Jan 24, 2011
- Primary completion
- Jan 25, 2019
- Results posted
- Yes
- Registry record
- NCT01169337 · updated Oct 1, 2026
Publications
linked from the registry- Lonial S, Jacobus S, Fonseca R, Weiss M, Kumar S, Orlowski RZ, Kaufman JL, Yacoub AM, Buadi FK, O'Brien T, Matous JV, Anderson DM, Emmons RV, Mahindra A, Wagner LI, Dhodapkar MV, Rajkumar SV. Randomized Trial of Lenalidomide Versus Observation in Smoldering Multiple Myeloma. J Clin Oncol. 2020 Apr 10;38(11):1126-1137. doi: 10.1200/JCO.19.01740. Epub 2019 Oct 25. PubMed 31652094