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Clinical trial · no report yet · Phase 3

GLORIOSA

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube41
Podcasts33

The trial

ClinicalTrials.gov
Official title
Randomized, Multicenter, Open-label, Phase 3 Study of Mirvetuximab Soravtansine in Combination With Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients With FRα-high Recurrent Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers Who Have Not Progressed After Second Line Platinum-based Chemotherapy Plus Bevacizumab
Phase
Phase 3
Status
Active not recruiting
Conditions
Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer
Interventions
Mirvetuximab soravtansine plus Bevacizumab; Bevacizumab
Arms
  • Arm 1 · Experimental
  • Arm 2 · Active comparator
Enrollment
520
Primary outcomes
  • Assess Progression-free survival (PFS)
Sponsor
AbbVie with GOG Foundation
Start
Mar 15, 2023
Primary completion
Apr 2027 (estimated)
Results posted
No
Registry record
NCT05445778 · updated Jun 2, 2026

Publications

linked from the registry
  • O'Malley DM, Myers T, Wimberger P, Van Gorp T, Redondo A, Cibula D, Nicum S, Rodrigues M, Backes FJ, Barlin JN, Lewin SN, Lim P, Pothuri B, Diver E, Banerjee S, Lorusso D. Maintenance with mirvetuximab soravtansine plus bevacizumab vs bevacizumab in FRalpha-high platinum-sensitive ovarian cancer. Future Oncol. 2024;20(32):2423-2436. doi: 10.1080/14796694.2024.2372241. Epub 2024 Jul 31. PubMed 39082675