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Clinical trial · no report yet · Phase 1
INCIPIENT
CARv3-TEAM-E T Cells in Glioblastoma
- NCT05660369 ↗
- Recruiting
- Marcela V. Maus, M.D.,Ph.D.
- Focused
We haven't built an HCP commentary report on INCIPIENT (CARv3-TEAM-E in glioblastoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on INCIPIENT so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 3 | |
| YouTube | 1 |
The trial
ClinicalTrials.gov- Official title
- INCIPIENT: INtraventricular CARv3-TEAM-E T Cells for PatIENTs With GBM
- Phase
- Phase 1
- Status
- Recruiting
- Conditions
- Glioblastoma; Malignant Glioma; Recurrent Glioblastoma; Recurrent Glioma
- Interventions
- CARv3-TEAM-E T cells
- Arms
- Safety Run-In Phase · Experimental
- Arm 1: Recurrent Glioblastoma (GBM), EGFRvIII Positive · Experimental
- Arm 2: Newly Diagnosed GBM, EGFRvIII Positive · Experimental
- Arm 3: Recurrent GBM, EGFRvIII Negative · Experimental
- Enrollment
- 21 (estimated)
- Primary outcomes
- Incidence of Adverse Events (AEs)
- Number of Dose-Limiting Toxicities (DLTs)
- Sponsor
- Marcela V. Maus, M.D.,Ph.D.
- Start
- Mar 22, 2023
- Primary completion
- Sep 1, 2026 (estimated)
- Results posted
- No
- Registry record
- NCT05660369 · updated Jul 14, 2026
Publications
linked from the registry- Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. N Engl J Med. 2024 Apr 11;390(14):1290-1298. doi: 10.1056/NEJMoa2314390. Epub 2024 Mar 13. PubMed 38477966