Erudio Healtherudio.com
Clinical trial · no report yet · Phase 3
INSIGNA
Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer
- NCT03793179 ↗
- Active, not recruiting
- National Cancer Institute (NCI)
- Deep
We haven't built an HCP commentary report on INSIGNA (pembrolizumab, carboplatin and 1 more in Lung Non-Squamous Non-Small Cell Carcinoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on INSIGNA so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 27 | |
| YouTube | 5 | |
| Podcasts | 3 |
The trial
ClinicalTrials.gov- Official title
- EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy Alone or in Combination With Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) With Immunobiomarker Signature-Driven Analysis
- Phase
- Phase 3
- Status
- Active, not recruiting
- Conditions
- Lung Non-Squamous Non-Small Cell Carcinoma; Stage IIIB Lung Cancer AJCC v8; Stage IIIC Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8
- Interventions
- Biospecimen Collection; Carboplatin; Computed Tomography; Magnetic Resonance Imaging; Pembrolizumab; Pemetrexed; Positron Emission Tomography
- Arms
- Arm A (pembrolizumab, pemetrexed, carboplatin) · Experimental
- Arm B (pembrolizumab, pemetrexed, carboplatin) · Experimental
- Arm C (pembrolizumab, pembrolizumab, carboplatin) · Active comparator
- Enrollment
- 600 (estimated)
- Primary outcomes
- Overall survival (OS)
- Sponsor
- National Cancer Institute (NCI)
- Start
- Apr 5, 2019
- Primary completion
- Sep 30, 2027 (estimated)
- Results posted
- No
- Registry record
- NCT03793179 · updated Oct 26, 2026