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Clinical trial · no report yet · Phase 3

KEYNOTE-630

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube9
Podcasts8
X threads5

The trial

ClinicalTrials.gov
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate Pembrolizumab Versus Placebo as Adjuvant Therapy Following Surgery and Radiation in Participants With High-risk Locally Advanced Cutaneous Squamous Cell Carcinoma (LA cSCC) (KEYNOTE-630)
Phase
Phase 3
Status
Terminated
Conditions
Carcinoma, Squamous Cell
Interventions
Pembrolizumab; Placebo
Arms
  • Pembrolizumab · Experimental
  • Placebo · Placebo comparator
Enrollment
450
Primary outcomes
  • Recurrence-Free Survival (RFS) as Assessed by the Investigator and Confirmed by Biopsy
Sponsor
Merck Sharp & Dohme LLC
Start
Apr 1, 2019
Primary completion
Jun 28, 2024
Results posted
Yes
Registry record
NCT03833167 · updated Sep 28, 2026