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Clinical trial · no report yet · Phase 1

MajesTEC-2

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

  • NCT04722146 ↗
  • Active not recruiting
  • Janssen Research & Development, LLC
  • 31 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
Podcasts17
YouTube11
X threads3

The trial

ClinicalTrials.gov
Official title
A Multi-arm Phase 1b Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Phase
Phase 1
Status
Active not recruiting
Conditions
Multiple Myeloma
Interventions
Teclistamab; Daratumumab; Pomalidomide; Lenalidomide; Bortezomib; Nirogacestat
Arms
  • Treatment Regimen A: Teclistamab + Daratumumab + Pomalidomide · Experimental
  • Treatment Regimen B: Teclistamab + Daratumumab + Lenalidomide + Bortezomib (21-day Cycles) · Experimental
  • Treatment Regimen C: Teclistamab + Nirogacestat · Experimental
  • Treatment Regimen D: Teclistamab + Lenalidomide · Experimental
  • Treatment Regimen E: Teclistamab + Daratumumab + Lenalidomide · Experimental
  • Treatment Regimen F: Teclistamab + Daratumumab + Lenalidomide + Bortezomib (28-day Cycles) · Experimental
Enrollment
140
Primary outcomes
  • Number of Participants with Incidence of Adverse Events (AEs)
  • Number of Participants with AEs by Severity
  • Number of Participants with Abnormalities in Laboratory Values
  • Number of Participants with Dose-Limiting Toxicity (DLT)
Sponsor
Janssen Research & Development, LLC
Start
Mar 12, 2021
Primary completion
Oct 3, 2025
Results posted
No
Registry record
NCT04722146 · updated Sep 28, 2026