Clinical trial · no report yet · Phase 3

MAVERICK

S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer

NCT04155034 ↗
Active, not recruiting
SWOG Cancer Research Network
Deep

We haven't built an HCP commentary report on MAVERICK (Extensive Stage Lung Small Cell Carcinoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Indexed commentary on MAVERICK so far

Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.

Channel	Indexed
X threads	58
Podcasts	5
YouTube	4
Bluesky threads	2

Indexed todayTypical once built

The trial

ClinicalTrials.gov

Official title: MRI Brain Surveillance Alone Versus MRI Surveillance and Prophylactic Cranial Irradiation (PCI): A Randomized Phase III Trial in Small-Cell Lung Cancer (MAVERICK)
Phase: Phase 3
Status: Active, not recruiting
Conditions: Extensive Stage Lung Small Cell Carcinoma; Limited Stage Lung Small Cell Carcinoma; Lung Small Cell Carcinoma
Interventions: Magnetic Resonance Imaging; Prophylactic Cranial Irradiation
Arms: Arm I (PCI, MRI) · Active comparator
Arm II (MRI) · Experimental
Enrollment: 668 (estimated)
Primary outcomes: Overall survival (OS)
Sponsor: SWOG Cancer Research Network with National Cancer Institute (NCI)
Start: May 4, 2020
Primary completion: Mar 17, 2026
Results posted: No
Registry record: NCT04155034 · updated Jun 11, 2026

Publications

linked from the registry

Schneiders FL, Senan S. New strategies for patients with limited-stage small-cell lung cancer. Lancet Respir Med. 2024 Oct;12(10):748-750. doi: 10.1016/S2213-2600(24)00223-6. Epub 2024 Aug 12. No abstract available. PubMed 39146945