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Clinical trial · no report yet · Phase 1

MonumenTAL-2

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

  • NCT05050097 ↗
  • Active not recruiting
  • Janssen Research & Development, LLC
  • 19 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube9
Podcasts5
X threads5

The trial

ClinicalTrials.gov
Official title
A Multi-arm Phase 1b Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma
Phase
Phase 1
Status
Active not recruiting
Conditions
Multiple Myeloma
Interventions
Talquetamab; Carfilzomib; Daratumumab SC; Lenalidomide; Pomalidomide
Arms
  • Treatment Regimen A: Talquetamab + Carfilzomib · Experimental
  • Treatment Regimen B: Talquetamab + Daratumumab + Carfilzomib · Experimental
  • Treatment Regimen C: Talquetamab + Lenalidomide · Experimental
  • Treatment Regimen D: Talquetamab + Daratumumab + Lenalidomide · Experimental
  • Treatment Regimen E: Talquetamab + Pomalidomide · Experimental
Enrollment
166
Primary outcomes
  • Number of Participants with Adverse Events (AEs) as a Measure of Safety and Tolerability
  • Number of Participants with AEs by Severity
  • Number of Participants with Clinically Significant Abnormalities in Laboratory Parameters
  • Number of Participants with Dose Limiting Toxicity (DLT)
Sponsor
Janssen Research & Development, LLC
Start
Sep 22, 2021
Primary completion
Mar 31, 2025
Results posted
No
Registry record
NCT05050097 · updated Sep 28, 2026