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Clinical trial · no report yet · Phase 1

MPN

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
Bluesky threads49

The trial

ClinicalTrials.gov
Official title
A Phase 1b Trial of Ivosidenib Combined With Ruxolitinib in IDH1-Mutated Advanced-Phase MPNs
Phase
Phase 1
Status
Recruiting
Conditions
Myeloproliferative Neoplasms
Interventions
Ivosidenib; Ruxolitinib
Arms
  • Dose Level -1 · Experimental
  • Dose Level 1 · Experimental
  • Dose Level 2 · Experimental
Enrollment
18 (estimated)
Primary outcomes
  • Maximum tolerated dose
Sponsor
University of Chicago
Start
Sep 19, 2024
Primary completion
May 2029 (estimated)
Results posted
No
Registry record
NCT06291987 · updated Sep 1, 2026