Clinical trial · no report yet · Phase 2
NCT01516216
Study of Vitamin D in Untreated Metastatic Colorectal Cancer
- NCT01516216 ↗
- Completed
- Dana-Farber Cancer Institute
- Deep
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| Bluesky threads | 116 |
The trial
ClinicalTrials.gov- Official title
- Randomized, Double-Blind, Phase II Trial of Vitamin D Supplementation in Patients With Previously Untreated Metastatic Colorectal Cancer
- Phase
- Phase 2
- Status
- Completed
- Conditions
- Metastatic Colorectal Cancer
- Interventions
- FOLFOX + bevacizumab; Vitamin D
- Arms
- Chemotherapy + Standard Dose Vitamin D · Active comparator
- Chemotherapy + Higher Dose · Active comparator
- Enrollment
- 139
- Primary outcomes
- Median Progression-free Survival (PFS)
- Sponsor
- Dana-Farber Cancer Institute
- Start
- Apr 13, 2012
- Primary completion
- Nov 9, 2019
- Results posted
- Yes
- Registry record
- NCT01516216 · updated Apr 26, 2022
Publications
linked from the registry- Ng K, Nimeiri HS, McCleary NJ, Abrams TA, Yurgelun MB, Cleary JM, Rubinson DA, Schrag D, Miksad R, Bullock AJ, Allen J, Zuckerman D, Chan E, Chan JA, Wolpin BM, Constantine M, Weckstein DJ, Faggen MA, Thomas CA, Kournioti C, Yuan C, Ganser C, Wilkinson B, Mackintosh C, Zheng H, Hollis BW, Meyerhardt JA, Fuchs CS. Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial. JAMA. 2019 Apr 9;321(14):1370-1379. doi: 10.1001/jama.2019.2402. PubMed 30964527