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Clinical trial · no report yet · Phase 2

NCT03290950

A Study of Daratumumab in Patients With Newly Diagnosed Multiple Myeloma

  • NCT03290950 ↗
  • Active, not recruiting
  • Memorial Sloan Kettering Cancer Center
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads3

The trial

ClinicalTrials.gov
Official title
Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Newly-Diagnosed Multiple Myeloma: A Clinical and Correlative Phase II Study
Phase
Phase 2
Status
Active, not recruiting
Conditions
Multiple Myeloma
Interventions
daratumumab; carfilzomib; lenalidomide; dexamethasone; dexamethasone
Arms
  • Cohort 1 · Experimental
  • Cohort 2 · Experimental
Enrollment
69
Primary outcomes
  • Best Overall Response
Sponsor
Memorial Sloan Kettering Cancer Center with Janssen Pharmaceuticals
Start
Sep 25, 2017
Primary completion
May 21, 2025
Results posted
Yes
Registry record
NCT03290950 · updated May 29, 2026

Publications

linked from the registry
  • Maura F, Boyle EM, Coffey D, Maclachlan K, Gagler D, Diamond B, Ghamlouch H, Blaney P, Ziccheddu B, Cirrincione A, Chojnacka M, Wang Y, Siegel A, Hoffman JE, Kazandjian D, Hassoun H, Guzman E, Mailankody S, Shah UA, Tan C, Hultcrantz M, Scordo M, Shah GL, Landau H, Chung DJ, Giralt S, Zhang Y, Arbini A, Gao Q, Roshal M, Dogan A, Lesokhin AM, Davies FE, Usmani SZ, Korde N, Morgan GJ, Landgren O. Genomic and immune signatures predict clinical outcome in newly diagnosed multiple myeloma treated with immunotherapy regimens. Nat Cancer. 2023 Dec;4(12):1660-1674. doi: 10.1038/s43018-023-00657-1. Epub 2023 Nov 9. PubMed 37945755