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Clinical trial · no report yet · Phase 2

NCT04468061

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
Bluesky threads4
X threads1

The trial

ClinicalTrials.gov
Official title
Saci-IO TNBC: Randomized Phase II Study of Sacituzumab Govitecan With or Without Pembrolizumab in PD-L1-negative Metastatic Triple Negative Breast Cancer (TNBC)
Phase
Phase 2
Status
Recruiting
Conditions
Breast Cancer; Triple Negative Breast Cancer; PD-L1 Negative
Interventions
Sacituzumab Govitecan; Pembrolizumab
Arms
  • Sacituzumab Govitecan + Pembrolizumab · Experimental
  • Sacituzumab Govitecan · Experimental
  • Retreatment · Experimental
Enrollment
110 (estimated)
Primary outcomes
  • Progression Free Survival (PFS)
Sponsor
Dana-Farber Cancer Institute with Gilead Sciences, Merck Sharp & Dohme LLC
Start
Jul 20, 2020
Primary completion
Apr 1, 2027 (estimated)
Results posted
No
Registry record
NCT04468061 · updated Apr 29, 2026

Publications

linked from the registry
  • Kwapisz D. Sacituzumab Govitecan-hziy in Breast Cancer. Am J Clin Oncol. 2022 Jul 1;45(7):279-285. doi: 10.1097/COC.0000000000000919. Epub 2022 May 12. PubMed 35728046