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Clinical trial · no report yet · Phase 1

NCT04634539

Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads5

The trial

ClinicalTrials.gov
Official title
IIT2020-02-Gong-GlutaPanc: Phase I Trial of First-line L-glutamine With Gemcitabine and Nab-paclitaxel in Advanced Pancreatic Cancer (GlutaPanc)
Phase
Phase 1
Status
Completed
Conditions
Advanced Pancreatic Adenocarcinoma; Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma
Interventions
Gemcitabine; Nab-paclitaxel; L-glutamine
Arms
  • Gemcitabine + Nab-paclitaxel + L-glutamine · Experimental
Enrollment
18
Primary outcomes
  • Recommended phase II dose (RP2D) of combination gemcitabine, nab-paclitaxel, and L-glutamine in treatment-naive metastatic pancreatic cancer.
Sponsor
Jun Gong, MD with Emmaus Medical, Inc.
Start
May 13, 2021
Primary completion
Jul 6, 2023
Results posted
No
Registry record
NCT04634539 · updated Aug 6, 2025

Publications

linked from the registry
  • Gong J, Muranaka H, Choi SY, Tighiouart M, Bhute S, Aja ER, Jacobs JP, Stotland A, Van Eyk J, Elmadbouh OHM, Edderkaoui M, Tanaka S, Furuya H, Osipov A, Lorber J, Billet S, Morris A, Ten Hoeve-Scott J, Graeber T, Pandol SJ, Hendifar A, Bhowmick NA. L-Glutamine in combination with first-line gemcitabine and nab-paclitaxel in advanced pancreatic ductal adenocarcinoma: an open-label, single-arm, phase 1 GlutaPanc trial. Nat Cancer. 2026 Aug 31. doi: 10.1038/s43018-026-01225-z. Online ahead of print. PubMed 42675216