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Clinical trial · no report yet · Phase 2

NCT05642780

SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
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The trial

ClinicalTrials.gov
Official title
A Multicenter, Open-label, Phase 2, Basket Study to Evaluate the Efficacy and Safety of SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors
Phase
Phase 2
Status
Active, not recruiting
Conditions
Solid Tumor
Interventions
SKB264; Pembrolizumab
Arms
  • cohort A · Experimental
  • cohort B · Experimental
  • cohort C · Experimental
  • cohort D · Experimental
  • Cohort E · Experimental
Enrollment
240 (estimated)
Primary outcomes
  • Dose limiting toxicity (DLT) and adverse events (AEs)
  • Objective Response Rate (ORR)
  • Prostate-specific antigen (PSA) response rate (Cohort D)
Sponsor
Klus Pharma Inc. with Myriad Genetics, Inc., Discovery Life Sciences, LLC, Ventana Medical Systems, Inc, Frontage Laboratories, Inc., Clario
Start
Jan 17, 2023
Primary completion
Nov 30, 2027 (estimated)
Results posted
No
Registry record
NCT05642780 · updated Oct 14, 2025