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Clinical trial · no report yet · Phase 2

NeoPACT

Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer

  • NCT03639948 ↗
  • Unknown
  • University of Kansas Medical Center
  • 38 commentary sources found
  • Standard

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube15
Podcasts15
X threads8

The trial

ClinicalTrials.gov
Official title
Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer
Phase
Phase 2
Status
Unknown
Conditions
Triple-negative Breast Cancer
Interventions
Carboplatin; Docetaxel; Pembrolizumab; Pegfilgrastim
Arms
  • Experimental: Carboplatin & Docetaxel plus Pembroluzimab · Experimental
Enrollment
120
Primary outcomes
  • Pathological Complete Response (pCR) Rate
Sponsor
University of Kansas Medical Center with Merck Sharp & Dohme LLC
Start
Sep 4, 2018
Primary completion
Jan 27, 2022
Results posted
Yes
Registry record
NCT03639948 · updated Apr 11, 2024

Publications

linked from the registry
  • Sharma P, Stecklein SR, Yoder R, Staley JM, Schwensen K, O'Dea A, Nye L, Satelli D, Crane G, Madan R, O'Neil MF, Wagner J, Larson KE, Balanoff C, Kilgore L, Phadnis MA, Godwin AK, Salgado R, Khan QJ, O'Shaughnessy J. Clinical and Biomarker Findings of Neoadjuvant Pembrolizumab and Carboplatin Plus Docetaxel in Triple-Negative Breast Cancer: NeoPACT Phase 2 Clinical Trial. JAMA Oncol. 2024 Feb 1;10(2):227-235. doi: 10.1001/jamaoncol.2023.5033. PubMed 37991778