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Clinical trial · no report yet · Phase 2

NERO

Niraparib Efficacy in Patient With Unresectable Mesothelioma

  • NCT05455424 ↗
  • Completed
  • University Hospital Southampton NHS Foundation Trust
  • 4 commentary sources found
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.

ChannelFound
Podcasts3
YouTube1

The trial

ClinicalTrials.gov
Official title
Niraparib Efficacy in Patient With Unresectable Mesothelioma: A Randomised Phase II Trial of Niraparib Versus Active Symptom Control in Patients With Previously Treated Mesothelioma
Phase
Phase 2
Status
Completed
Conditions
Mesothelioma, Malignant
Interventions
Niraparib Oral Product; Active Symptom Control
Arms
  • Niraparib + ASC · Experimental
  • Active Symptom Control · Active comparator
Enrollment
88
Primary outcomes
  • Progression-free survival
Sponsor
University Hospital Southampton NHS Foundation Trust with University of Southampton, British Lung Foundation
Start
Jul 11, 2022
Primary completion
Jan 31, 2025
Results posted
No
Registry record
NCT05455424 · updated May 15, 2025

Publications

linked from the registry
  • Fennell D, Griffiths D, Eminton Z, Morgan-Fox A, Hill K, Ewings S, Stuart C, Johnson L, Mallard K, Nye M, Darlison L, Dulloo S, Cave J, Luo JL, Taylor P, Spicer J, Poile C, Bzura A, Griffiths G. Evaluating niraparib versus active symptom control in patients with previously treated mesothelioma (NERO): a study protocol for a multicentre, randomised, two-arm, open-label phase II trial in UK secondary care centres. BMJ Open. 2023 Nov 22;13(11):e073120. doi: 10.1136/bmjopen-2023-073120. PubMed 37993149