Clinical trial · no report yet · Phase not applicable
NORDIC-SUN
Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-Trial
- NCT03977571 ↗
- Recruiting
- Niels Fristrup
- Standard
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| X threads | 14 | |
| Bluesky threads | 1 |
The trial
ClinicalTrials.gov- Official title
- Multicenter Randomized Trial of Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma Receiving Checkpoint Inhibitors: a Trial Evaluating the Impact of Surgery or No Surgery. The NORDIC-SUN-Trial
- Phase
- Phase not applicable
- Status
- Recruiting
- Conditions
- Kidney Cancer; Renal Cell Carcinoma Metastatic; Synchronous Neoplasm
- Interventions
- Cytoreductive nephrectomy; Tissue sampling
- Arms
- Deferred nephrectomy · Experimental
- No surgery · Active comparator
- Enrollment
- 400 (estimated)
- Primary outcomes
- Overall survival
- Sponsor
- Niels Fristrup with Aarhus University Hospital
- Start
- Jul 6, 2020
- Primary completion
- Dec 1, 2028 (estimated)
- Results posted
- No
- Registry record
- NCT03977571 · updated Sep 23, 2026
Publications
linked from the registry- Flammia RS, Campi R, Bologna E, Bertolo R, Leonardo C, Calabro F, Amparore D, Simone G; Young Academic Urologists (YAU) Renal Cancer Working Group. Cytoreductive nephrectomy in the era of immune-checkpoint inhibitors: back to the future? BJU Int. 2026 May;137(5):763-769. doi: 10.1111/bju.70168. Epub 2026 Feb 11. PubMed 41673778
- Iisager L, Ahrenfeldt J, Donskov F, Ljungberg B, Bex A, Lund L, Lyskjaer I, Fristrup N. Multicenter randomized trial of deferred cytoreductive nephrectomy in synchronous metastatic renal cell carcinoma receiving checkpoint inhibitors: the NORDIC-SUN-Trial. BMC Cancer. 2024 Feb 24;24(1):260. doi: 10.1186/s12885-024-11987-3. PubMed 38402173
- Kuusk T, Abu-Ghanem Y, Mumtaz F, Powles T, Bex A. Perioperative therapy in renal cancer in the era of immune checkpoint inhibitor therapy. Curr Opin Urol. 2021 May 1;31(3):262-269. doi: 10.1097/MOU.0000000000000868. PubMed 33742979