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Clinical trial · no report yet · Phase 2

PERSEVERE

Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube46
Podcasts30
X threads24
Bluesky threads1
X videos1

The trial

ClinicalTrials.gov
Official title
A Phase II Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer (PERSEVERE)
Phase
Phase 2
Status
Terminated
Conditions
Breast Cancer; Triple Negative Breast Cancer
Interventions
Capecitabine; Talazoparib; Pembrolizumab; Inavolisib
Arms
  • Arm 1 · Experimental
  • Arm 2 · Active comparator
  • Arm 3 · Active comparator
Enrollment
52
Primary outcomes
  • ARM 1c: Disease Free Survival (DFS) at 2 Years
Sponsor
Bryan Schneider, MD with Genentech, Inc., Pfizer, Foundation Medicine, Indiana University, Vera Bradley Foundation for Breast Cancer
Start
Aug 24, 2021
Primary completion
Oct 24, 2024
Results posted
Yes
Registry record
NCT04849364 · updated May 31, 2025