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Clinical trial · no report yet · Phase 1/Phase 2

RADIAN

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma

  • NCT05784012 ↗
  • Active, not recruiting
  • Grupo Español de Tratamiento de Tumores de Cabeza y Cuello
  • Focused

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
YouTube3
X threads2
Podcasts1

The trial

ClinicalTrials.gov
Official title
Phase Ib/II Non-randomized Non-comparative Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma
Phase
Phase 1/Phase 2
Status
Active, not recruiting
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
Dostarlimab; Niraparib; cisplatin plus radiotherapy; Niraparib
Arms
  • Cohort A · Experimental
  • Cohort B · Experimental
Enrollment
34
Primary outcomes
  • 1-year disease free survival
Sponsor
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello with GlaxoSmithKline, MFAR
Start
Nov 13, 2023
Primary completion
Mar 2027 (estimated)
Results posted
No
Registry record
NCT05784012 · updated Jun 4, 2026