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Clinical trial · no report yet · Phase 3
RADIATE-LM
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
- NCT06500481 ↗
- Recruiting
- NRG Oncology
- Focused
We haven't built an HCP commentary report on RADIATE-LM (breast or non-small cell lung cancer leptomeningeal metastasis; tests no drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on RADIATE-LM so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 3 | |
| Podcasts | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase III Randomized Clinical Trial of Proton Craniospinal Irradiation Versus Involved-Field Radiotherapy for Patients With Breast Cancer or Non-Small Cell Lung Cancer Leptomeningeal Metastasis (Radiate-LM)
- Phase
- Phase 3
- Status
- Recruiting
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Breast Carcinoma; Metastatic Lung Non-Small Cell Carcinoma; Metastatic Malignant Neoplasm in the Leptomeninges; Stage IV Lung Cancer AJCC v8
- Interventions
- Biospecimen Collection; Computed Tomography; Involved-Field Radiation Therapy; Lumbar Puncture; Magnetic Resonance Imaging; Positron Emission Tomography; Proton Beam Craniospinal Irradiation; Quality-of-Life Assessment
- Arms
- Arm 1 (IFRT) · Active comparator
- Arm 2 (pCSI) · Experimental
- Enrollment
- 115 (estimated)
- Primary outcomes
- Overall survival (OS)
- Sponsor
- NRG Oncology
- Start
- Mar 4, 2025
- Primary completion
- Jul 31, 2028 (estimated)
- Results posted
- No
- Registry record
- NCT06500481 · updated Aug 17, 2026