Clinical trial · no report yet · Phase 4
REDOSE
Effect of a Reduced Dose Enzalutamide in Frail (m)CRPC Patients on Cognitive Side Effects
- NCT03927391 ↗
- Completed
- Radboud University Medical Center
- 23 commentary sources found
- Standard
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Commentary we found
Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.
| Channel | Found | |
|---|---|---|
| Podcasts | 14 | |
| YouTube | 8 | |
| X threads | 1 |
The trial
ClinicalTrials.gov- Official title
- Effect of a Reduced Dose on Cognitive Side Effects of Enzalutamide in Frail (Metastatic) Castration-resistant Prostate Cancer Patients (REDOSE)
- Phase
- Phase 4
- Status
- Completed
- Conditions
- Prostatic Neoplasms, Castration-Resistant
- Interventions
- Enzalutamide
- Arms
- reference (normal) dose · Active comparator
- test (reduced) dose · Experimental
- Enrollment
- 57
- Primary outcomes
- To determine the change in the CNS side effect fatigue* in frail (m)CRPC patients treated with a reduced dose of enzalutamide (120mg OD) compared to the standard dose of enzalutamide (160mg OD) after 6 weeks of treatment.
- Sponsor
- Radboud University Medical Center
- Start
- May 30, 2019
- Primary completion
- Jan 8, 2024
- Results posted
- No
- Registry record
- NCT03927391 · updated Jun 12, 2024
Publications
linked from the registry- Boerrigter E, Overbeek JK, Benoist GE, Somford DM, Hamberg P, Tol J, Scholtes B, Willemsen AECAB, Buffart LM, Kessels RPC, Mehra N, van Oort IM, van Erp NP. A Prospective Randomised Trial to Determine the Effect of a Reduced Versus Standard Dose of Enzalutamide on Side Effects in Frail Patients with Prostate Cancer. Eur Urol Oncol. 2024 Dec;7(6):1376-1383. doi: 10.1016/j.euo.2024.02.009. Epub 2024 Mar 13. PubMed 38485614