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Clinical trial · no report yet · Phase 2

ReVenG

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube12
Podcasts9
X threads2
X videos1

The trial

ClinicalTrials.gov
Official title
A Multicenter, Open-Label, Phase 2 Study to Evaluate the Efficacy and Safety of Venetoclax-Obinutuzumab Retreatment in Patients With Recurring Chronic Lymphocytic Leukemia
Phase
Phase 2
Status
Recruiting
Conditions
Chronic Lymphocytic Leukemia (CLL)
Interventions
Venetoclax; Obinutuzumab
Arms
  • Cohort 1 - venetoclax + obinutuzumab · Experimental
  • Cohort 2 - venetoclax + obinutuzumab · Experimental
Enrollment
75 (estimated)
Primary outcomes
  • Overall response (OR) in Cohort 1 after end of combination treatment
Sponsor
AbbVie with F. Hoffmann-La Roche Ltd; German CLL Study Group (GCLLSG); Dana-Farber Cancer Institute
Start
Mar 28, 2022
Primary completion
Nov 2026 (estimated)
Results posted
No
Registry record
NCT04895436 · updated Feb 9, 2026

Publications

linked from the registry
  • Castonguay M, Anderson MA, Thompson P, Seymour JF. Venetoclax retreatment in chronic lymphocytic leukemia is biologically rational and clinically effective. Blood Adv. 2026 May 26;10(10):3357-3366. doi: 10.1182/bloodadvances.2026019871. PubMed 41843779