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Clinical trial · no report yet · Phase 3
RTOG 1112
Sorafenib Tosylate With or Without Stereotactic Body Radiation Therapy in Treating Patients With Liver Cancer
- NCT01730937 ↗
- Completed
- Radiation Therapy Oncology Group
- Deep
We haven't built an HCP commentary report on RTOG 1112 (sorafenib in Adult Primary Hepatocellular Carcinoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on RTOG 1112 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 109 | |
| YouTube | 7 | |
| Podcasts | 6 | |
| Bluesky threads | 3 | |
| X videos | 3 |
The trial
ClinicalTrials.gov- Official title
- Randomized Phase III Study of Sorafenib Versus Stereotactic Body Radiation Therapy Followed by Sorafenib in Hepatocellular Carcinoma
- Phase
- Phase 3
- Status
- Completed
- Conditions
- Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer
- Interventions
- Sorafenib; stereotactic body radiation therapy
- Arms
- Sorafenib Alone · Active comparator
- SBRT followed by Sorafenib · Experimental
- Enrollment
- 193
- Primary outcomes
- Overall Survival
- Sponsor
- Radiation Therapy Oncology Group with National Cancer Institute (NCI), NRG Oncology
- Start
- Apr 2013
- Primary completion
- Jul 1, 2022
- Results posted
- Yes
- Registry record
- NCT01730937 · updated Jan 28, 2026
Publications
linked from the registry- Dawson LA, Winter KA, Knox JJ, Zhu AX, Krishnan S, Guha C, Kachnic LA, Gillin MT, Hong TS, Craig TD, Williams TM, Hosni A, Chen E, Noonan AM, Koay EJ, Sinha R, Lock MI, Ohri N, Dorth JA, Delouya G, Swaminath A, Moughan J, Crane CH. Stereotactic Body Radiotherapy vs Sorafenib Alone in Hepatocellular Carcinoma: The NRG Oncology/RTOG 1112 Phase 3 Randomized Clinical Trial. JAMA Oncol. 2025 Feb 1;11(2):136-144. doi: 10.1001/jamaoncol.2024.5403. PubMed 39699905