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Clinical trial · no report yet · Phase 3
SAVOIR
Savolitinib vs. Sunitinib in MET-driven PRCC.
- NCT03091192 ↗
- Active, not recruiting
- AstraZeneca
- Standard
We haven't built an HCP commentary report on SAVOIR (savolitinib and sunitinib in Carcinoma) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on SAVOIR so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 12 | |
| YouTube | 6 | |
| Podcasts | 3 |
The trial
ClinicalTrials.gov- Official title
- A Phase III, Open Label, Randomised, Controlled, Multi-Centre Study To Assess the Efficacy and Safety of Savolitinib Versus Sunitinib in Patients With MET-Driven, Unresectable and Locally Advanced, Or Metastatic Papillary Renal Cell Carcinoma (PRCC)
- Phase
- Phase 3
- Status
- Active, not recruiting
- Conditions
- Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Urologic Neoplasms; Kidney Diseases; Neoplasms by Site; Enzyme Inhibitors; Protein Kinase Inhibitors
- Interventions
- Savolitinib; Sunitinib
- Arms
- Savolitinib · Experimental
- Sunitinib · Active comparator
- Enrollment
- 60
- Primary outcomes
- Progression Free Survival (PFS) by Blinded Independent Central Review (BICR)
- Sponsor
- AstraZeneca with Hutchison Medipharma Limited
- Start
- Jul 25, 2017
- Primary completion
- Aug 18, 2019
- Results posted
- Yes
- Registry record
- NCT03091192 · updated Jul 14, 2026
Publications
linked from the registry- Choueiri TK, Heng DYC, Lee JL, Cancel M, Verheijen RB, Mellemgaard A, Ottesen LH, Frigault MM, L'Hernault A, Szijgyarto Z, Signoretti S, Albiges L. Efficacy of Savolitinib vs Sunitinib in Patients With MET-Driven Papillary Renal Cell Carcinoma: The SAVOIR Phase 3 Randomized Clinical Trial. JAMA Oncol. 2020 Aug 1;6(8):1247-1255. doi: 10.1001/jamaoncol.2020.2218. PubMed 32469384
- Maia MC, Salgia M, Pal SK. Harnessing cell-free DNA: plasma circulating tumour DNA for liquid biopsy in genitourinary cancers. Nat Rev Urol. 2020 May;17(5):271-291. doi: 10.1038/s41585-020-0297-9. Epub 2020 Mar 17. PubMed 32203306