Clinical trial · no report yet · Phase 3
SKYSCRAPER-02
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
- NCT04256421 ↗
- Completed
- Hoffmann-La Roche
- Standard
We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Preliminary discovery
Commentary in our index that names this trial so far
Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.
| Channel | Found | |
|---|---|---|
| X threads | 8 | |
| Podcasts | 2 | |
| YouTube | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase III, Randomized, Double-Blind, Placebo-Controlled Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab (Anti-Tigit Antibody) in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
- Phase
- Phase 3
- Status
- Completed
- Conditions
- Small Cell Lung Cancer
- Interventions
- Tiragolumab; Atezolizumab; Carboplatin; Etoposide; Placebo
- Arms
- Placebo + Atezolizumab + CE · Active comparator
- Tiragolumab + Atezolizumab + CE · Experimental
- Enrollment
- 490
- Primary outcomes
- Investigator-assessed Progression-free Survival (PFS) in the Primary Analysis Set (PAS)
- Overall Survival (OS) in the PAS
- Sponsor
- Hoffmann-La Roche
- Start
- Feb 4, 2020
- Primary completion
- Sep 6, 2022
- Results posted
- Yes
- Registry record
- NCT04256421 · updated Apr 3, 2026
Publications
linked from the registry- Rudin CM, Liu SV, Soo RA, Lu S, Hong MH, Lee JS, Bryl M, Dumoulin DW, Rittmeyer A, Chiu CH, Ozyilkan O, Johnson M, Navarro A, Novello S, Ozawa Y, Tam SH, Patil NS, Wen X, Huang M, Hoang T, Meng R, Reck M. SKYSCRAPER-02: Tiragolumab in Combination With Atezolizumab Plus Chemotherapy in Untreated Extensive-Stage Small-Cell Lung Cancer. J Clin Oncol. 2024 Jan 20;42(3):324-335. doi: 10.1200/JCO.23.01363. Epub 2023 Nov 17. PubMed 37976444