SKYSCRAPER-05
A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer
- NCT04832854 ↗
- Terminated
- Hoffmann-La Roche
- Focused
We haven't built an HCP commentary report on SKYSCRAPER-05 (atezolizumab, tiragolumab and 5 more in Non-Small Cell Lung Cancer (NSCLC)) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on SKYSCRAPER-05 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 6 | |
| Podcasts | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase II, Open-Label, Multicenter Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Patients With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer
- Phase
- Phase 2
- Status
- Terminated
- Conditions
- Non-Small Cell Lung Cancer (NSCLC)
- Interventions
- Atezolizumab; Tiragolumab; Carboplatin; Cisplatin; Pemetrexed; Gemcitabine; Paclitaxel
- Arms
- Cohort A (PD-L1 High) · Experimental
- Cohort B (PD-L1 All Comers) · Experimental
- Enrollment
- 50
- Primary outcomes
- Number of Participants With Surgical Delays
- Number of Participants With Operative and Post-operative Complications
- Number of Participants With Surgical Cancellations Related to Study Treatment
- Number of Participants With Adverse Events (AEs)
- Major Pathological Response (MPR) Rate
- Sponsor
- Hoffmann-La Roche
- Start
- Apr 23, 2021
- Primary completion
- Mar 5, 2025
- Results posted
- Yes
- Registry record
- NCT04832854 · updated Mar 11, 2026