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Clinical trial · no report yet · Phase 2/Phase 3

STELLAR-311

Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built. Commentary is thin so far, so the report would be short.

ChannelFound
YouTube5
Podcasts2

The trial

ClinicalTrials.gov
Official title
A Phase 2/3, Multicenter, Randomized Open-Label Study of Zanzalintinib vs Everolimus in Participants With Previously Treated, Unresectable, Locally Advanced or Metastatic Neuroendocrine Tumors
Phase
Phase 2/Phase 3
Status
Recruiting
Conditions
Pancreatic Neuroendocrine Tumor (pNET); Extra-Pancreatic Neuroendocrine Tumor (epNET)
Interventions
Zanzalintinib; Everolimus
Arms
  • Everolimus · Active comparator
  • Zanzalintinib · Experimental
Enrollment
440 (estimated)
Primary outcomes
  • Progression-Free Survival (PFS) Per Response Evaluation Criteria in Solid Tumors Version (RECIST) 1.1 as Assessed by Blinded Independent Central Review (BICR)
Sponsor
Exelixis
Start
Jul 21, 2025
Primary completion
Jun 30, 2029 (estimated)
Results posted
No
Registry record
NCT06943755 · updated Sep 29, 2026

Publications

linked from the registry
  • Chan JA, Strosberg JR, Yoo C, Singh S, Huang H, Goel M, Scheffold C, Capdevila J. STELLAR-311: a randomized phase II/III study of zanzalintinib versus everolimus in advanced neuroendocrine tumors. Future Oncol. 2026 Sep 28:1-8. doi: 10.1080/14796694.2026.2733790. Online ahead of print. PubMed 42803451