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Clinical trial · no report yet · Phase 3

SUCCESSOR-1

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube26
Podcasts12
X threads4
X videos2

The trial

ClinicalTrials.gov
Official title
A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing Mezigdomide (CC-92480), Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM): SUCCESSOR-1
Phase
Phase 3
Status
Recruiting
Conditions
Relapsed or Refractory Multiple Myeloma
Interventions
mezigdomide; Pomalidomide; Bortezomib; Dexamethasone
Arms
  • MeziVd (mezigdomide, bortezomib and dexamethasone) · Experimental
  • PVd (pomalidomide, bortezomib and dexamethasone) · Experimental
Enrollment
810 (estimated)
Primary outcomes
  • Progression-free Survival (PFS)
Sponsor
Celgene
Start
Sep 20, 2022
Primary completion
Jan 10, 2027 (estimated)
Results posted
No
Registry record
NCT05519085 · updated Sep 30, 2026