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Clinical trial · no report yet · Phase 1/Phase 2
Symbiotic-GU-06 trial: what clinicians have said so far
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
- NCT07421700 ↗
- Recruiting
- Pfizer
- Focused size, estimated: 1–150 verified statements once built
We haven't built an HCP commentary report on Symbiotic-GU-06 (PF-08634404; PF-08634404 plus enfortumab vedotin in locally advanced or metastatic urothelial cancer) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on Symbiotic-GU-06 so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Indexed so far | |
|---|---|
| 3 posts on X, typically up to 13 once built |
The trial
ClinicalTrials.gov- Official title
- AN INTERVENTIONAL PHASE 1B/2, OPEN-LABEL STUDY TO INVESTIGATE THE SAFETY, ANTITUMOR ACTIVITY, AND PHARMACOKINETICS OF PF 08634404 MONOTHERAPY OR IN COMBINATION WITH ENFORTUMAB VEDOTIN IN ADULT PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER
- Phase
- Phase 1/Phase 2
- Status
- Recruiting
- Conditions
- Urothelial Cancer; Advanced/Metastatic Urothelial Cancer; Urothelial Carcinoma
- Interventions
- PF-08634404; Enfortumab Vedotin
- Arms
- Cohort A · Experimental
- Cohort B · Experimental
- Enrollment
- 132 (estimated)
- Primary outcomes
- Confirmed Objective Response Rate (ORR) by investigator
- Number of Participants with Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)
- Number of participants with dose limiting toxicity (DLT) in Part 1 of Cohort B
- Sponsor
- Pfizer with Astellas Pharma Inc
- Start
- Mar 11, 2026
- Primary completion
- Dec 28, 2027 (estimated)
- Results posted
- No
- Registry record
- NCT07421700 · updated Oct 8, 2026