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Clinical trial · no report yet · Phase 2

TITAN-RCC

Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Renal Cell Carcinoma

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Preliminary discovery

Commentary in our index that names this trial so far

Podcasts, YouTube videos and X posts we have indexed. A report screens them, searches for more and cites what clinicians said when it is built, so final coverage is set at build.

ChannelFound
X threads17
Podcasts3
YouTube2

The trial

ClinicalTrials.gov
Official title
A Phase II Single Arm Clinical Trial of a Tailored ImmunoTherapy Approach With Nivolumab in Subjects With Metastatic or Advanced Renal Cell Carcinoma
Phase
Phase 2
Status
Completed
Conditions
Carcinoma, Renal Cell; Clear-cell Metastatic Renal Cell Carcinoma
Interventions
Nivolumab/Ipilimumab
Arms
  • Nivolumab/Ipilimumab · Experimental
Enrollment
200
Primary outcomes
  • Objective Response Rate (ORR)
Sponsor
AIO-Studien-gGmbH with Bristol-Myers Squibb
Start
Oct 2016
Primary completion
Oct 2021
Results posted
No
Registry record
NCT02917772 · updated Oct 6, 2022

Publications

linked from the registry
  • Grimm MO, Esteban E, Barthelemy P, Schmidinger M, Busch J, Valderrama BP, Charnley N, Schmitz M, Schumacher U, Leucht K, Foller S, Baretton G, Duran I, de Velasco G, Priou F, Maroto P, Albiges L; TITAN-RCC study group. Tailored immunotherapy approach with nivolumab with or without nivolumab plus ipilimumab as immunotherapeutic boost in patients with metastatic renal cell carcinoma (TITAN-RCC): a multicentre, single-arm, phase 2 trial. Lancet Oncol. 2023 Nov;24(11):1252-1265. doi: 10.1016/S1470-2045(23)00449-7. Epub 2023 Oct 13. PubMed 37844597