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Clinical trial · no report yet · Phase 3
TNTCRT
Total Neoadjuvant Treatment vs. Chemoradiotherapy in Local Advanced Rectal Cancer With High Risk Factors
- NCT03177382 ↗
- Unknown
- West China Hospital
- Focused
We haven't built an HCP commentary report on TNTCRT (high-risk locally advanced rectal cancer; tests no drug) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on TNTCRT so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| X threads | 7 | |
| Podcasts | 1 |
The trial
ClinicalTrials.gov- Official title
- Total Neoadjuvant Treatment Versus Conventional Neo-chemoradiotherapy in Locally Advanced Rectal Cancer With High Risk Factors: a Multicenter Randomized Phase III Clinical Study.
- Phase
- Phase 3
- Status
- Unknown
- Conditions
- Total Neoadjuvant Treatment; Chemoradiotherapy; Local Advanced Rectal Cancer; High Risk Factors
- Interventions
- Total neoadjuvant treatment; concurrent chemoradiotherapy; TME; Adjuvant chemotherapy
- Arms
- Total neoadjuvant treatment · Experimental
- concurrent chemoradiotherapy group · Active comparator
- Enrollment
- 458 (estimated)
- Primary outcomes
- disease free survival
- Sponsor
- West China Hospital
- Start
- Jun 15, 2017
- Primary completion
- May 30, 2021 (estimated)
- Results posted
- No
- Registry record
- NCT03177382 · updated May 8, 2018
Publications
linked from the registry- Wang X, Tang Y, Lu J, Meng W, Liu P, Zhou J, Wen F, Ding P, Li J, Wang B, Guo Q, Qiu J, Sun H, Deng X, Shen Y, Zeng H, Jiang D, Wang D, Li Y, Xiao Y, Wang Z. Total Neoadjuvant Therapy With Long-Course Radiotherapy Versus Chemoradiotherapy in High-Risk Locally Advanced Rectal Cancer (TNTCRT): A Multicenter, Randomized, Phase III Trial. J Clin Oncol. 2026 Jul 23:JCO2503110. doi: 10.1200/JCO-25-03110. Online ahead of print. PubMed 42492015