TRILLIUM
A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy
- NCT06456463 ↗
- Active, not recruiting
- Stemline Therapeutics, Inc.
- Focused
We haven't built an HCP commentary report on TRILLIUM (tagraxofusp plus venetoclax plus azacitidine in previously untreated CD123+ acute myeloid leukemia) yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.
Indexed commentary on TRILLIUM so far
Podcasts, YouTube videos and X posts we have indexed that name the trial. It is where a report starts, not where it ends: the build searches for more, so finished reports usually cover more than this.
| Channel | Indexed | |
|---|---|---|
| YouTube | 1 | |
| Podcasts | 1 | |
| X threads | 1 |
The trial
ClinicalTrials.gov- Official title
- A Phase II Multicenter Open-label Trial of Tagraxofusp (Tag) in Combination With Venetoclax and Azacitidine (Ven/Aza) in Adults With Previously Untreated CD123+ Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy
- Phase
- Phase 2
- Status
- Active, not recruiting
- Conditions
- Acute Myeloid Leukemia
- Interventions
- Tagraxofusp; Venetoclax; Azacitidine
- Arms
- Part 1 - Tagraxofusp (9 μg/kg/day) · Experimental
- Part 1 - Tagraxofusp (12 μg/kg/day) · Experimental
- Part 2 - Tagraxofusp (Selected Dose) and TP53 Wild Type · Experimental
- Part 2 - Tagraxofusp (Selected Dose) and TP53 Mutated · Experimental
- Enrollment
- 85
- Primary outcomes
- Part 1: Determination of Part 2 Selected Dose of Tagraxofusp When Administered in Combination with Venetoclax and Azacitidine
- Part 2: Number of Participants Achieving a Best Overall Response (BOR) of Complete Remission (CR)
- Sponsor
- Stemline Therapeutics, Inc.
- Start
- Jan 14, 2025
- Primary completion
- Feb 9, 2028 (estimated)
- Results posted
- No
- Registry record
- NCT06456463 · updated Aug 6, 2026