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Clinical trial · no report yet · Phase 3

ZUMA-23

Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma

  • NCT05605899 ↗
  • Active not recruiting
  • Kite, A Gilead Company
  • 63 commentary sources found
  • Deep

We haven't built a report for this trial yet. This page shows the registry record and the public commentary we found that names the trial. A report reads that commentary and sets out what clinicians said about the trial, each point linked to its source. How reports are made.

Commentary we found

Podcasts, YouTube videos and X posts in our index that name this trial. A report screens them, searches for more and cites what clinicians said when it is built.

ChannelFound
YouTube32
Podcasts20
X threads11

The trial

ClinicalTrials.gov
Official title
An Adaptive Phase 3, Randomized, Open-Label, Multicenter Study to Compare the Efficacy and Safety of Axicabtagene Ciloleucel Versus Standard of Care Therapy as First-Line Therapy in Subjects With High-Risk Large B-Cell Lymphoma (ZUMA-23)
Phase
Phase 3
Status
Active not recruiting
Conditions
High-risk Large B-cell Lymphoma (LBCL)
Interventions
Axicabtagene Ciloleucel; Cyclophosphamide; Fludarabine; Etoposide; Rituximab; Doxorubicin; Vincristine; Prednisone
Arms
  • Axicabtagene Ciloleucel · Experimental
  • Standard of Care Therapy · Active comparator
Enrollment
300 (estimated)
Primary outcomes
  • Event-free Survival (EFS) by Blinded Central Assessment
Sponsor
Kite, A Gilead Company
Start
Feb 10, 2023
Primary completion
Mar 2031 (estimated)
Results posted
No
Registry record
NCT05605899 · updated Apr 15, 2026